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Endocrine Abstracts

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ea0056p640 | Diabetes (to include epidemiology, pathophysiology) | ECE2018

The 4-hydroxynonenal mediated oxidative damage of blood proteins and lipids involves secondary lipid peroxidation reactions

Alfaqih Mahmoud A. , Mustafa Ayman G. , Al-shboul Othman

Lipid peroxidation is linked with several metabolic diseases. Lipid peroxidation causes cellular damage through reactive aldehyde species such as 4-hydroxyonenal (4-HNE). The exact mechanism(s) by which 4-HNE causes damage in the intravascular compartment is not exactly known. Using an in vitro system, we investigated the damage induced by 4-HNE on the blood by measuring protein carbonyl groups and thiobarbituric acid reactive substances (TBARS) following 4-HNE treatm...
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Published by BioScientifica

Endocrine Abstracts
ISSN 1470-3947 (print) | ISSN 1479-6848 (online)
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